শনিবার, ৭ সেপ্টেম্বর, ২০১৩

A hormone to make tooth removal much less painful

New york city, July 14-- Removal of teeth can quickly come to be far much less unpleasant utilizing a biochemical stemmed from a human hormone.

University of Florida specialists are examining the power of a human hormone called relaxin to biochemically get rid of the teeth faster and with much less pain throughout treatment, records science portal www.scienceagogo.com.
Orthodontics traditionally apply force against a tooth to move it.
The researchers are testing the power of relaxin, the hormone that helps women's pelvic ligaments stretch in preparation for giving birth.

That ability prompted them to consider relaxin as a possible way to accelerate tooth movement and prevent relapse, a condition where the tooth migrates back to its original position after braces are removed, it said.

"Ours is the first study to use a naturally occurring hormone, recombinant human relaxin, to biochemically augment tooth movement and retention," said researcher Timothy Wheeler.

Most of the problems associated with orthodontic treatments have to do with the body's natural elastins resisting manipulation.

"You can imagine normal collagen and elastin fibres to be like rubber bands that attach to the tooth to hold it in place," said Wheeler. "Those tissue fibres resist the force of the orthodontic treatment applied to move the tooth, and, when that force is removed, say when the braces are taken off, the elasticity of the tissues springs the tooth back into position." 

Researchers plan to inject relaxin into the gums to loosen the normal collagen and elastin fibres.
Once the teeth have been moved, researchers will administer another injection of relaxin under the premise that it will further soften gum tissue fibres, preventing them from pulling teeth back into their original position.
Wheeler said researchers hope to determine whether the treatment could eliminate the need for patients to wear retainers to hold teeth in place after braces are removed.  Here are some more findings on before and after braces.

"Right now, retention is the biggest problem we have in orthodontics," Wheeler said. "I want to get completely away from retainers, which for most patients right now are a lifetime commitment."

The drug was given the green light last April from the Food and Drug Administration. 

Relaxin does nothing to numb the pain that often lingers after orthodontic treatment.

Published by HT Syndication with permission from Indo-Asian News Service.

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